Z-L(D-Val)G-CHN2

MedChem Express

Z-L(D-Val)G-CHN2

14

Research Use Only

99.35

C22H31N5O5

445.51

Z-L(D-Val)G-CHN2 is the isoform of Z-LVG-CHN2 (HY-108137). Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase . Z-LVG-CHN2 is a tripeptide derivative and mimics part of the human cysteine proteinase-binding center. Z-LVG-CHN2 displays an inhibition on HSV whereas no significant effect on poliovirus replication. Z-LVG-CHN2 effectively blocks SARS-COV-2 replication ( EC 50 =190 nM) via inhibition of SARS-COV-2 3CL pro protease [3] .

O=C(N[C@@H](C(NCC(C=[N+]=[N-])=O)=O)C(C)C)[C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O

-20°C

12352200