Z-L(D-Val)G-CHN2

TargetMol Chemicals

Z-L(D-Val)G-CHN2

999

Chemical

Research Use Only

Z-L(D-Val)G-CHN2

C22H31N5O5

445.51

Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase. This tripeptide derivative emulates a segment of the human cysteine proteinase-binding center and demonstrates selective antiviral activity, inhibiting herpes simplex virus (HSV) yet exhibiting negligible impact on poliovirus replication. Notably, Z-LVG-CHN2 effectively impedes SARS-CoV-2 replication with an EC50 value of 190 nM by targeting the SARS-CoV-2 3CL protease [3].

3 years

-20°C

12352200