(Z)-Mirin

MedChem Express

(Z)-Mirin [1198097-97-0]

10

1198097-97-0

Research Use Only

99.30

C10H8N2O2S

220.25

(Z)-Mirin is an MRN (Mre11-Rad50-Nbs1) inhibitor. (Z)-Mirin prevents MRN-dependent activation of ATM without affecting ATM protein kinase activity. (Z)-Mirin inhibits Mre11-associated exonuclease activity. (Z)-Mirin increases apoptosis , triggers a G2/M checkpoint and strongly inhibits homology-directed repair (HDR) [1] [2] .

O=C1N=C(N)S/C1=C\C2=CC=C(O)C=C2

-20°C,2°C to 8°C

12352200