Z-Phe-Arg-AFC [93753-73-2] [93753-73-2]

AdipoGen Life Sciences

Z-Phe-Arg-AFC [93753-73-2] [93753-73-2]

10

93753-73-2

Research Use Only

>95%

C33H33F3N6O6 . C2HF3O2

666.7 . 114.0

Chemical. CAS: 93753-73-2 (free base). Formula: C33H33F3N6O6 . C2HF3O2. MW: 666.7 . 114.0. Synthetic. Fluorogenic substrate, specifically used to determine the enzyme activity of Cathepsin L. Useful for the study of cathepsin activity and for screening small molecule inhibitors for drug discovery and HTS applications. Likely to be cleaved by cathepsins B, F, K, S and L, cathepsins L-like proteases and proteases such as papain, cruzipain, plasma kallikrein, soybean trypsin-like enzyme and the falcipains-1 and -2 (malaria hemoglobinases). Hydrolysis of this substrate is monitored by observing fluorescence at an Excitation of 400nm and Emission at 505nm. - Fluorogenic substrate, specifically used to determine the enzyme activity of Cathepsin L. Useful for the study of cathepsin activity and for screening small molecule inhibitors for drug discovery and HTS applications. Likely to be cleaved by cathepsins B, F, K, S and L, cathepsins L-like proteases and proteases such as papain, cruzipain, plasma kallikrein, soybean trypsin-like enzyme and the falcipains-1 and -2 (malaria hemoglobinases). Hydrolysis of this substrate is monitored by observing fluorescence at an Excitation of 400nm and Emission at 505nm.

[NH3+]C(NCCC[C@@H](C(NC1=CC=C(C(C(F)(F)F)=CC(O2)=O)C2=C1)=O)NC([C@H](CC3=CC=CC=C3)NC(OCC4=CC=CC=C4)=O)=O)=N.FC(F)(C([O-])=O)F

-20°C,2°C to 8°C

12352200