Z-Pro-Pro-aldehyde-dimethyl acetal [170116-63-9]

TargetMol Chemicals

Z-Pro-Pro-aldehyde-dimethyl acetal [170116-63-9]

16

Chemical

Research Use Only

Z-Pro-Pro-aldehyde-dimethyl acetal

C20H28N2O5

376.45

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance lies in its role in modulating cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimers disease [1] [2].

3 years

C(=O)(N1[C@H](C(OC)OC)CCC1)[C@H]2N(C(OCC3=CC=CC=C3)=O)CCC2

-20°C

12352200