(Z)-RG-13022 [149286-90-8]

TargetMol Chemicals

(Z)-RG-13022 [149286-90-8]

16

Chemical

Research Use Only

(Z)-RG-13022

C16H14N2O2

266.29

(Z)-RG-13022 is a tyrosine kinase (TK) inhibitor that preferentially inhibits the TK activity of the EGF receptor, restricting the EGF-stimulated growth of cultured cells. It demonstrates an IC50 of 11 microM for DNA synthesis in HN5 cells, showcasing thrice the potency of its isomer, (E)-RG-13022 (IC50 = 38 microM). This compound is applied in breast cancer cell research [1] [2].

3 years

C(=C(\C#N)/C=1C=CC=NC1)\C2=CC(OC)=C(OC)C=C2

-20°C

12352200