Chemical. Formula: C35H47N7O7 . C2HF3O2. MW: 677.8 . 114.0. Proteasome subunit alpha type-1 (Macropain) substrate used for assaying the trypsin-like activity of the 20S proteasome. Cysteine proteinase falcipain-2 and falcipain-3 (malarial hemoglobinases) substrate. Cathepsin S substrate. Hydrolysis of this fluorogenic peptide substrate is monitored by observing fluorescence at an Excitation of 345nm and Emission at 445nm. - Proteasome subunit alpha type-1 (Macropain) substrate used for assaying the trypsin-like activity of the 20S proteasome. Cysteine proteinase falcipain-2 and falcipain-3 (malarial hemoglobinases) substrate. Cathepsin S substrate. Hydrolysis of this fluorogenic peptide substrate is monitored by observing fluorescence at an Excitation of 345nm and Emission at 445nm.