Z-VDVAD-AFC

MedChem Express

Z-VDVAD-AFC

14

Research Use Only

C39H45F3N6O13

862.80

Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].

FC(F)(C(C1=CC=C(NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)C=C1O3)=CC3=O)F

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