Zatebradine

MedChem Express

Zatebradine [85175-67-3]

10

85175-67-3

Research Use Only

99.27

C26H36N2O5

456.57

Zatebradine (UL-FS-49 (free base); UL-FS-49CL (free base)) is a potent inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels with an IC 50 value of 1.96 microM. Zatebradine blocks the slow inward current through human HCN1 , HCN2 , HCN3 and HCN4 channels , with IC 50 values of 1.83 microM, 2.21 microM, 1.90 microM and 1.88 microM, respectively [1] .

O=C1N(CCCN(CCC2=CC=C(OC)C(OC)=C2)C)CCC3=CC(OC)=C(OC)C=C3C1

-20°C,2°C to 8°C

12352200