Zavolosotine [2604416-66-0]

TargetMol Chemicals

Zavolosotine [2604416-66-0]

9

Research Use Only

C20H18F5N5O

439.38

Zavolosotine (Compound 1) is a potent agonist of the somatostatin receptor type 5 (SST5), with an EC50 of less than 1 nM. It effectively inhibits the secretion of insulin and glucagon, while elevating blood glucagon levels in a rat model.

C(N[C@H](C(F)(F)F)C)(=O)C1=C(C(=C(C#N)N=C1)C2=CC(F)=CC(F)=C2)N3CC[C@H](N)C3

-20°C

12352200