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ProductsBack/ZC3HAV1 antibody [N3C2], Internal

ZC3HAV1 antibody [N3C2], Internal

GTX120134
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetZC3HAV1
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Overview

  • Supplier
    GeneTex
  • Product Name
    ZC3HAV1 antibody [N3C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.35 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID56829
  • Target name
    ZC3HAV1
  • Target description
    zinc finger CCCH-type containing, antiviral 1
  • Target synonyms
    ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; FLB6421; inactive Poly [ADP-ribose] polymerase 13; PARP13; ZAP; ZC3H2; ZC3HDC2; zinc finger CCCH domain-containing protein 2; zinc finger CCCH-type antiviral protein 1; zinc finger CCCH-type, antiviral 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ7Z2W4
  • Protein Name
    Zinc finger CCCH-type antiviral protein 1
  • Scientific Description
    This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function.
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  • Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist. Okudera M et al., 2021 Dec 22, Neuroimmunomodulation
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  • S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies. Kmiec D et al., 2021 Oct, PLoS Pathog
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  • Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets. Rodriguez KM et al., 2021 Jan 21, Elife
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  • SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans. Nchioua R et al., 2020 Oct 16, mBio
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  • CpG Frequency in the 5 Third of the env Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein. Kmiec D et al., 2020 Jan 14, mBio
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  • Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein. Chiu HP et al., 2018 Jul, PLoS Pathog
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  • Expression of short hairpin RNAs using the compact architecture of retroviral microRNA genes. Burke JM et al., 2017 Sep 29, Nucleic Acids Res
    Read more