Western Blot analysis of A549, K562 and PC3 cell using ZFP42 Polyclonal Antibody at dilution of 1:500
ZFP42 Polyclonal Antibody
E-AB-13003
Product group Antibodies
Overview
- SupplierElabscience
- Product NameZFP42 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionRex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.
- UNSPSC12352203