Zidovudine-13C,d3

MedChem Express

Zidovudine-13C,d3

10

Research Use Only

C9 13CH10D3N5O4

271.25

Zidovudine-13C,d3 is the 13C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-13C,d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C1N(C=C(C(N1)=O)[13C]([2H])([2H])[2H])[C@]2([H])C[C@H]([C@@H](O2)CO)N=[N+]=[N-]

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