ZIKV-IN-1

MedChem Express

ZIKV-IN-1

10

Research Use Only

C21H18BrF2N3O3

478.29

ZIKV-IN-1 is a potent zika virus inhibitor with an EC50 of 2.8 microM and EC90 of 6.8 microM. ZIKV-IN-1 shows anti-ZIKV activity with low cytotoxicity. ZIKV-IN-1 shows a strong affinity to ZIKV RdRp domain[1]. ZIKV-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CC1=NC=NC2=C1C(C#CC3=CC(F)=C(C=C3)Br)=CN2[C@@H]4O[C@@H]([C@H]([C@]4(F)C)O)CO

12352200