ZL0580

MedChem Express

ZL0580 [2377151-10-3]

9

2377151-10-3

Research Use Only

99.26

C25H23F3N4O4S

532.53

ZL0580, a structurally close analog of ZL0590, induces epigenetic suppression of HIV via selectively binding to BD1 domain of BRD4 . ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter [1] [2] [3] .

O=C(NC1=CC=C(S(N2CCC[C@H]2C(NC3=CC=CC=C3)=O)(=O)=O)C=C1)NC4=CC=C(C(F)(F)F)C=C4

-20°C,2°C to 8°C

12352200