ZNRF3 Antibody, HRP conjugated
CSB-PA890933HB01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetZNRF3
Overview
- SupplierCusabio
- Product NameZNRF3 Antibody, HRP conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateHRP
- Gene ID84133
- Target nameZNRF3
- Target descriptionzinc and ring finger 3
- Target synonymsBK747E2.3; CTA-292E10.6; E3 ubiquitin-protein ligase ZNRF3; novel C3HC4 type Zinc finger (ring finger); RING finger protein 203; RING-type E3 ubiquitin transferase ZNRF3; RNF203; zinc/RING finger protein 3
- HostRabbit
- IsotypeIgG
- Protein IDQ9ULT6
- Protein NameE3 ubiquitin-protein ligase ZNRF3
- Scientific DescriptionE3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203