1-Deoxysphingosine (m18:1(14Z)) [2190487-94-4]

TargetMol Chemicals

1-Deoxysphingosine (m18:1(14Z)) [2190487-94-4]

16

Chemical

Research Use Only

1-Deoxysphingosine (m18:1(14Z))

C18H37NO

283.5

1-Deoxysphingosine (m18:1(14Z)) is an unconventional sphingolipid featuring a (14Z) double bond at the n-4 position, synthesized when serine palmitoyltransferase combines palmitoyl-CoA with alanine, not serine, during sphingolipid production. Unlike typical sphingolipids, it lacks the essential C1-hydroxyl group for standard degradation but undergoes metabolism by cytochrome P450 (CYP) subfamilies CYP4A and CYP4F in MEF cells.

3 years

C(CC[C@H]([C@H](C)N)O)CCCCCCC/C=C\CCC

-20°C

12352200