1-Monopalmitin [542-44-9]

MedChem Express

1-Monopalmitin [542-44-9]

10

542-44-9

Research Use Only

99.42

C19H38O4

330.51

1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC50=50-58 microg/mL), with low toxicity to normal cells[1][2].

OC(CO)COC(CCCCCCCCCCCCCCC)=O

-20°C,2°C to 8°C

12352200