1-Naphthohydroxamic acid [6953-61-3]
T13996
CAS Number6953-61-3
Product group Chemicals
Molecular Weight187.19
Overview
- SupplierTargetMol Chemicals
- Product Name1-Naphthohydroxamic acid
- Delivery Days Customer4
- CAS Number6953-61-3
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical Name1-Naphthohydroxamic acid
- Molecular FormulaC11H9NO2
- Molecular Weight187.19
- Scientific Description1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 microM, demonstrating greater selectivity for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 microM). It does not increase global histone H4 acetylation or reduce total intracellular HDAC activity but can induce tubulin acetylation[1][2].
- Shelf life instruction3 years
- SMILESONC(=O)c1cccc2ccccc12
- Storage Instruction-20°C
- UNSPSC12352200
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