ProductsBack/1-Palmitoyl-2-oleoyl-sn-glycero-3-PE [26662-94-2]

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE [26662-94-2]

Name: 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE [26662-94-2]
SKU: HY-W583868_M09
Availability: BackOrder

HY-W583868

Product group Molecular Biology

Overview

Supplier
MedChem Express
Product Name
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE [26662-94-2]
Delivery Days Customer
5
CAS Number
26662-94-2
Certification
Research Use Only
Estimated Purity
99.46
Molecular Formula
C39H76NO8P
Molecular Weight
718.00
Scientific Description
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines[1][2].
SMILES
CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(O)(OCCN)=O)COC(CCCCCCCCCCCCCCC)=O)=O
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
41115811