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ProductsBack/1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe [154436-49-4]

1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe [154436-49-4]

HY-115701
MedChem Express
CAS Number154436-49-4
Product group Chemicals
Molecular Weight800.05
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Overview

  • Supplier
    MedChem Express
  • Product Name
    1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe [154436-49-4]
  • Delivery Days Customer
    5
  • CAS Number
    154436-49-4
  • Certification
    Research Use Only
  • Molecular Formula
    C43H78NO10P
  • Molecular Weight
    800.05
  • Scientific Description
    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 microM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
  • SMILES
    O=C(CCC/C=C\C/C=C\C/C=C\C=C\[C@@H](OO)CCCCC)O[C@H](COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCN)(O)=O
  • UNSPSC
    12352200

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