10-Gingerol

MedChem Express

10-Gingerol [23513-15-7]

10

23513-15-7

Research Use Only

99.66

C21H34O4

350.49

10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC 50 value of 10.47 microM against DPPH radical, an IC 50 value of 1.68 microM against superoxide radical and an IC 50 value of 1.35 microM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC 50 of 12.1 microM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol is promising for research of ulcerative colitis [1] [2] [3] [4] [5] .

CCCCCCCCC[C@H](O)CC(CCC1=CC=C(O)C(OC)=C1)=O

-20°C

12352200