10-Hydroxy-2-decenoic acid [765-01-5]

MedChem Express

10-Hydroxy-2-decenoic acid [765-01-5]

5

765-01-5

Research Use Only

99.99

C10H18O3

186.25

10-Hydroxy-2-decenoic acid (10-HDA) is an orally active unsaturated medium-chain fatty acid with various physiological activities. 10-Hydroxy-2-decenoic acid induces ROS-mediated apoptosis in A549 cells. 10-Hydroxy-2-decenoic acid inhibits VEGF-induced angiogenesis in human venous endothelial cells. 10-Hydroxy-2-decenoic acid alleviates non-alcoholic fatty liver disease (NAFLD) by activating the AMPK-alpha signaling pathway. 10-Hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-kappaB signaling downstream of FFAR4. 10-Hydroxy-2-decenoic acid is an antibiotic against many bacteria and fungi, such as Neurospora sitophila, molds and Staphylococcus aureus. 10-Hydroxy-2-decenoic acid has longevity-promoting effects in C. elegans. 10-Hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl beta hydroxylase and inhibiting chondrocyte senescence[1][2][3][4][5][6][7][8][9][10].

O=C(O)/C=C/CCCCCCCO

-20°C,2°C to 8°C

12352200