11-cis-Retinoic Acid-d5

MedChem Express

11-cis-Retinoic Acid-d5

10

Research Use Only

C20H23D5O2

305.47

11-cis-Retinoic Acid-d5 is the deuterium labeled Retinoic acid. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARalpha/beta/gamma. Retinoic acid bind to PPARbeta/delta with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2].

OC(/C=C(C)/C=C\C=C(C)\C=C\C1=C(C([2H])([2H])[2H])C([2H])([2H])CCC1(C)C)=O

12131703