1,10-Phenanthroline, Monohydrate
27713
CAS Number5144-89-8
Product group Chemicals
Estimated Purity≥99%
Molecular Weight198.2 Da
Overview
- SupplierBPS Bioscience
- Product Name1,10-Phenanthroline, Monohydrate
- Delivery Days Customer7
- CAS Number5144-89-8
- CertificationResearch Use Only
- Estimated Purity≥99%
- Format0.5M solution in anhydrous DMSO (100X)
- Molecular FormulaC12H8N2 H2O
- Molecular Weight198.2 Da
- Scientific Description1,10-phenanthroline (o-phenanthroline) is a chelator with high affinity for divalent metal ions. When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions. While not specific for DUBs, it has been shown to be a potent inhibitor of JAMM-type isopeptidases through chelation of the active site Zn2+ ion. As such, o-phenanthroline is widely used when preparing cell lysates for enrichment of proteins bearing K63-linked polyubiquitin chains which are especially sensitive to DUBs in the JAMM family.
- Storage Instruction-20°C,RT
- UNSPSC12352200