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1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose [120143-22-8]

HY-154318
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose [120143-22-8]
  • Delivery Days Customer
    10
  • CAS Number
    120143-22-8
  • Certification
    Research Use Only
  • Molecular Formula
    C17H19N3O7
  • Molecular Weight
    377.35
  • Scientific Description
    1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • SMILES
    [N-]=[N+]=N[C@H]1[C@@H](OC(C)=O)C(OC(C)=O)O[C@@H]1COC(C2=CC=C(C)C=C2)=O
  • UNSPSC
    41115811