12-HETE [71030-37-0]

MedChem Express

12-HETE [71030-37-0]

10

71030-37-0

Research Use Only

312.04 uM

95.70

C20H32O3

320.47

12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-kappaB through the integrin-linked kinase (ILK) pathway[1].12-HETE has both anti-thrombotic and pro-thrombotic effects[2]. 12-HETE is a neuromodulator[3].

CCCCC/C=C\CC(O)/C=C/C=C\C/C=C\CCCC(O)=O

-20°C

12352200