12-HETE-d8 [2525175-25-9]

MedChem Express

12-HETE-d8 [2525175-25-9]

10

2525175-25-9

Research Use Only

304.40 uM

98.0

C20H24D8O3

328.52

12-HETE-d8 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-kappaB through the integrin-linked kinase (ILK) pathway[1].12-HETE has both anti-thrombotic and pro-thrombotic effects[2]. 12-HETE is a neuromodulator[3].

CCCCC/C([2H])=C(CC([2H])(/C([2H])=C/C([2H])=C(C/C([2H])=C(CCCC(O)=O)/[2H])/[2H])O)/[2H]

-20°C

12352200