12-OxoETE

Biorbyt

12-OxoETE

10

108437-64-5

Research Use Only

98.00%

C20H30O3

318.457

12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via a leukotriene B4 receptor or a common activation sequence.

CCCCC\C=C/CC(=O)\C=C\C=C/C\C=C/CCCC(O)=O

-20°C

12352200