12R-LOX-IN-2

Biorbyt

12R-LOX-IN-2

10

Research Use Only

99.84%

C19H13NO

271.31

12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 may be useful in the study of psoriasis and other skin-associated inflammatory diseases.

OC=1C=CC(C2=NC=3C=CC=CC3C=C2)=C4C=CC=CC14

-20°C

12352200