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14-3-3 sigma antibody

Name: 14-3-3 sigma antibody
SKU: GTX100289_G10
Availability: BackOrder

GTX100289

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetSFN

Overview

Supplier
GeneTex
Product Name
14-3-3 sigma antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID2810
Target name
SFN
Target description
stratifin
Target synonyms
YWHAS, 14-3-3 protein sigma, epithelial cell marker protein 1
Host
Rabbit
Isotype
IgG
Protein IDP31947
Protein Name
14-3-3 protein sigma
Scientific Description
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. p53-regulated inhibitor of G2/M progression.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Wang X, Yamamoto Y, Imanishi M, et al. Enhanced G1 arrest and apoptosis via MDM4/MDM2 double knockdown and MEK inhibition in wild-type TP53 colon and gastric cancer cells with aberrant KRAS signaling. Oncol Lett. 2021,22(1):558. doi: 10.3892/ol.2021.12819
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Qin X, Qiu F, Zou Z. TRIM25 is associated with cisplatin resistance in non-small-cell lung carcinoma A549 cell line via downregulation of 14-3-3σ. Biochem Biophys Res Commun. 2017,493(1):568-572. doi: 10.1016/j.bbrc.2017.08.151
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Chen YJ, Tsai WH, Chen YL, et al. Epstein-Barr virus (EBV) Rta-mediated EBV and Kaposi's sarcoma-associated herpesvirus lytic reactivations in 293 cells. PLoS One. 2011,6(3):e17809. doi: 10.1371/journal.pone.0017809
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