14-3-3 sigma antibody
GTX100289
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSFN
Overview
- SupplierGeneTex
- Product Name14-3-3 sigma antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2810
- Target nameSFN
- Target descriptionstratifin
- Target synonyms14-3-3 protein sigma; epithelial cell marker protein 1; YWHAS
- HostRabbit
- IsotypeIgG
- Protein IDP31947
- Protein Name14-3-3 protein sigma
- Scientific DescriptionAdapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. p53-regulated inhibitor of G2/M progression.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Enhanced G1 arrest and apoptosis via MDM4/MDM2 double knockdown and MEK inhibition in wild-type TP53 colon and gastric cancer cells with aberrant KRAS signaling. Wang X et al., 2021 Jul, Oncol LettRead more
- TRIM25 is associated with cisplatin resistance in non-small-cell lung carcinoma A549 cell line via downregulation of 14-3-3sigma. Qin X et al., 2017 Nov 4, Biochem Biophys Res CommunRead more
- Epstein-Barr virus (EBV) Rta-mediated EBV and Kaposis sarcoma-associated herpesvirus lytic reactivations in 293 cells. Chen YJ et al., 2011 Mar 10, PLoS OneRead more
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