1400W [180001-34-7]

MedChem Express

1400W [180001-34-7]

102

180001-34-7

Research Use Only

98.49

h315, h319, h320

C10H15N3

177.25

1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a Kd value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation[1][2].

CC(NCC1=CC=CC(CN)=C1)=N

-20°C,2°C to 8°C

12352200