14,15-Dehydro Leukotriene B4 [114616-11-4]

MedChem Express

14,15-Dehydro Leukotriene B4 [114616-11-4]

5

114616-11-4

Research Use Only

C20H30O4

334.45

14,15-Dehydro Leukotriene B4 (Compound 4) is a LTB4 receptor antagonist. 14,15-Dehydro Leukotriene B4 also has a higher binding affinity for BLT1 with a Ki value of 27 nM and BLT2 with a Ki value of 473 nM. 14,15-Dehydro Leukotriene B4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 microM[1][2].

CCCCCC#CC[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O

12352200