15-Deoxy-delta-12,14-prostaglandin J2

MedChem Express

15-Deoxy-delta-12,14-prostaglandin J2 [87893-55-8]

9

87893-55-8

Research Use Only

3.16 mM

99.0

C20H28O3

316.43

15-Deoxy-delta-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-delta-12,14-prostaglandin J2 is a selective PPARgamma ( EC 50 of 2 microM) and a covalent PPARdelta agonist. 15-Deoxy-delta-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC 50 of 7 microM [1] [2] .

CCCCC/C=C/C=C1[C@H](C=CC\1=O)C/C=C\CCCC(O)=O

-20°C

12352200