1,5-Isoquinolinediol [5154-02-9]

TargetMol Chemicals

1,5-Isoquinolinediol [5154-02-9]

10

5154-02-9

Chemical

Research Use Only

1,5-Isoquinolinediol

99.43%

C9H7NO2

161.16

1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 microM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.

3 years

Oc1cccc2c(O)nccc12

-20°C

12352200