15-OxoEDE [105835-44-7]

TargetMol Chemicals

15-OxoEDE [105835-44-7]

16

105835-44-7

Chemical

Research Use Only

15-OxoEDE

C20H34O3

322.5

15-OxoEDE, generated through the oxidation of 15-HEDE, effectively inhibits 5-LO in RBL-1 cells with an IC50 of 55 microM, approximately half as potent as 15(S)-HEDE. Additionally, another related oxo-eicosanoid, 5-oxoETE, is produced from 5(S)-HETE via a specific dehydrogenase, exhibiting significant inflammatory activity.

3 years

C(=C/C=C\CCCCCCCCCC(O)=O)\C(CCCCC)=O

-20°C

12352200