15(R)-15-methyl Prostaglandin F2alpha [35864-81-4]

TargetMol Chemicals

15(R)-15-methyl Prostaglandin F2alpha [35864-81-4]

16

35864-81-4

Chemical

Research Use Only

15(R)-15-methyl Prostaglandin F2alfa

C21H36O5

368.514

15(R)-15-methyl PGF2alpha, a metabolically stable analog of PGF2alpha, is an inactive, prodrug PGF agonist intended for activation by gastric acid through oral administration. This transformation involves acid-catalyzed epimerization that converts 15(R)-15-methyl PGF2alpha into its active counterpart, the 15(S)-isomer. Upon conversion, the 15(S)-isomer has been shown to induce luteolysis in rhesus monkeys following an approximately 12 mg/animal dosage, a response not observed with the 15(R)-isomer.

3 years

CCCCC[C@@](C)(O)\C=C\[C@H]1[C@H](O)C[C@H](O)C1C\C=C/CCCC(O)=O

-20°C

12352200