16-Dehydropregnenolone acetate [979-02-2]

MedChem Express

16-Dehydropregnenolone acetate [979-02-2]

5

979-02-2

CHEMICAL,general_chemicals_reagents

Research Use Only

C23H32O3

356.50

16-Dehydropregnenolone acetate (16-DPA), a sterols compound, is an orally active 17alpha-hydroxylase and 5alpha-reductase inhibitor. 16-Dehydropregnenolone is also a potent bile acid receptor (BAR)/farnesoid X receptor (FXR) antagonist. 16-Dehydropregnenolone hypolipidemic and anticancer effects. 16-Dehydropregnenolone acetate (16-DPA) is the drug intermediate that can be used for synthesis of Dexamethasone (HY-14648) and related other steroidal pharmacophores[1][2][3].

CC(C1=CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(C)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O

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