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(+/-)16-HETE

ORB1985157
Biorbyt
CAS Number128914-46-5
Product group Chemicals
Estimated Purity98.00%
Molecular Weight320.473
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Overview

  • Supplier
    Biorbyt
  • Product Name
    (+/-)16-HETE
  • Delivery Days Customer
    10
  • CAS Number
    128914-46-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.00%
  • Molecular Formula
    C20H32O3
  • Molecular Weight
    320.473
  • Scientific Description
    Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (+/-)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, however 16(S)-HETE does not affect perfusion pressure. At a concentration of 2 microM the (S)-enantiomer of 16-HETE inhibits proximal tubule ATPase activity by as much as 60%, whereas the (R)-isomer has negligible effects on ATPase activity.
  • SMILES
    CCCCC(O)\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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