16,16-dimethyl Prostaglandin A2 [41691-92-3]

TargetMol Chemicals

16,16-dimethyl Prostaglandin A2 [41691-92-3]

16

41691-92-3

Chemical

16,16-dimethyl Prostaglandin A2

C22H34O4

362.5

16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 microg/ml. Daily infusion of 10 microg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.

3 years

C(=C/[C@H](C(CCCC)(C)C)O)\[C@@H]1[C@@H](C/C=C\CCCC(O)=O)C(=O)C=C1

-20°C

12352200