16alpha-Hydroxyprednisolone [13951-70-7]

MedChem Express

16alpha-Hydroxyprednisolone [13951-70-7]

10

13951-70-7

Research Use Only

99.78

C21H28O6

376.44

16alpha-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16alpha-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16alpha-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily[1][2].

O=C1C=C[C@@]2([C@]3([C@H](C[C@@]4([C@](O)([C@@H](C[C@]4([C@@]3(CCC2=C1)[H])[H])O)C(CO)=O)C)O)[H])C

2°C to 8°C

12352200