16(S)-Iloprost [74843-14-4]

TargetMol Chemicals

16(S)-Iloprost [74843-14-4]

44

74843-14-4

Research Use Only

16(S)-Iloprost

C22H32O4

360.49

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(S)-Iloprost potently inhibits platelet aggregation with an IC50 value of 3.5 nM.

3 years

C(=C/[C@H]([C@H](CC#CC)C)O)\[C@@H]1[C@@]2([C@@](C/C(=C\CCCC(O)=O)/C2)(C[C@H]1O)[H])[H]

-20°C

12352200