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(+/-)17-HDHA

ORB1985041
Biorbyt
CAS Number90780-52-2
Product group Chemicals
Estimated Purity98.00%
Molecular Weight344.495
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Overview

  • Supplier
    Biorbyt
  • Product Name
    (+/-)17-HDHA
  • Delivery Days Customer
    10
  • CAS Number
    90780-52-2
  • Certification
    Research Use Only
  • Estimated Purity
    98.00%
  • Molecular Formula
    C22H32O3
  • Molecular Weight
    344.495
  • Scientific Description
    (+/-)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17(S)-HDHA could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of mammalian 15-LOs. 17(S)-HDHA was shown to be an inhibitor of U-46619 -induced rabbit and rat aortic smooth muscle contraction with IC50 values of 4.9 and 7.2 microM, respectively. (+/-)17-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.
  • SMILES
    CC\C=C/CC(O)\C=C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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