2-Azido-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxyuridine [177980-10-8]
HY-154423
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name2-Azido-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxyuridine [177980-10-8]
- Delivery Days Customer10
- CAS Number177980-10-8
- CertificationResearch Use Only
- Molecular FormulaC30H29N5O7
- Molecular Weight571.58
- Scientific Description2-Azido-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2-Azido-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO[C@H]1[C@@H](N=[N+]=[N-])[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5
- UNSPSC41115811