2-beta-C-Ethynyl-5-methyluridine

MedChem Express

2-beta-C-Ethynyl-5-methyluridine

10

Research Use Only

C12H14N2O6

282.25

2-beta-C-Ethynyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2-beta-C-Ethynyl-5-methyluridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O[C@]([C@@H]1O)([C@H](N(C(N2)=O)C=C(C)C2=O)O[C@@H]1CO)C#C

41115811