2-Chloro-2-deoxy-6-O-methylinosine [146196-07-8]

MedChem Express

2-Chloro-2-deoxy-6-O-methylinosine [146196-07-8]

10

146196-07-8

Research Use Only

C11H13ClN4O4

300.70

2-Chloro-2-deoxy-6-O-methylinosine is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].

O[C@@H]1[C@@H](CO)O[C@H](C1)N(C=N2)C3=C2C(OC)=NC(Cl)=N3

41115811