2-Chloroadenosine-5-O-diphosphate sodium [82927-78-4]

TargetMol Chemicals

2-Chloroadenosine-5-O-diphosphate sodium [82927-78-4]

44

Chemical

Research Use Only

2-Chloroadenosine-5'-O-diphosphate sodium

C10H11ClN5O10P2.3Na

527.59

2-Chloroadenosine-5-O-diphosphate, a purine nucleotide adenosine 5diphosphate (ADP) derivative, demonstrates multiple biological activities. It promotes aggregation and inhibits cyclic AMP (cAMP) production, triggered by prostaglandin E2 (PGE2), in a concentration-dependent manner within isolated human platelet-rich plasma. Additionally, this compound facilitates the relaxation of precontracted isolated guinea pig taenia coli strips (pD2 = 6.74) and reduces arterial blood pressure in rats. Moreover, 2-Chloroadenosine-5-O-diphosphate significantly inhibits the ATPase activity of mortalin, a member of the heat shock protein 70 (Hsp70) family, with an apparent Ki of 45.05 microM for the human enzyme.

3 years

O[C@@H]1[C@H](O)[C@@H](COP([O-])(OP([O-])([O-])=O)=O)O[C@H]1N2C=NC3=C(N)N=C(Cl)N=C32.[Na+].[Na+].[Na+]

-20°C

12352200