2-Cyanoethylalsterpaullone [852527-97-0]

MedChem Express

2-Cyanoethylalsterpaullone [852527-97-0]

5

852527-97-0

Research Use Only

C19H14N4O3

346.34

2-Cyanoethylalsterpaullone (compound 7) is an Alsterpaullone (HY-108359) derivative, which exhibits potent and selective inhibitory activities against CDK1/Cyclin B and GSK-3beta (GSK-3beta: IC50=0.8 nM; CDK1/Cyclin B: IC50=0.23 nM)[1].

N#CCCC1=CC=C(NC(CC2=C3NC4=C2C=C([N+]([O-])=O)C=C4)=O)C3=C1

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