2-Deoxy-2-fluorouridine [784-71-4]

MedChem Express

2-Deoxy-2-fluorouridine [784-71-4]

10

784-71-4

Research Use Only

99.96

C9H11FN2O5

246.19

2-Deoxy-2-fluorouridine is a derivative of the pyrimidine nucleoside uridine. 2-Deoxy-2-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. Hepatitis C polyU/UC RNA strands containing 2-Deoxy-2-fluorouridine, bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells. 2-Deoxy-2-fluorouridine also has been used as a starting material in the synthesis of respiratory syncytial virus (RSV) polymerase inhibitors. 2-Deoxy-2-fluorouridine can incorporate into DNA and RNA in rat and woodchuck model upon administration. 2-Deoxy-2-fluorouridine can be studied in anti-viral research[1][2][3][4].

O[C@H]1[C@@H](F)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO

-20°C,2°C to 8°C

12352200