2-Deoxyuridine [951-78-0]

MedChem Express

2-Deoxyuridine [951-78-0]

10

951-78-0

Research Use Only

99.98

C9H12N2O5

228.204

2-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2-deoxyuridine, EdU (HY-118411). 2-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Abeta25-35-induced brain injury, which is promising for research of Alzheimers disease (AD)[1][2][3].

O=C(N1)N([C@H]2C[C@H](O)[C@@H](CO)O2)C=CC1=O

-20°C,2°C to 8°C

12352200